Because the IOL market now includes presbyopia-correcting technologies, as well as other premium design enhancements, that are rapidly growing segments of the market, we feature a detailed discussion of these IOLs, both current market offerings and the numerous technologies in the development pipeline. We also explore IOL injectors, examining injector types, makers and models, and injector trends. We provide context for understanding market trends and forecasts by discussing cataracts and their prevalence, methods of cataract extraction, a global view of cataract surgery and cataract surgery providers, reimbursement issues, presbyopia and refractive lens exchange, and IOL design enhancements. Our final chapter profiles the companies involved in the IOL market.

The 2008 Comprehensive Report on the Global IOL Market was published in June 2008. This spiral-bound, full-color, 303-page report is chockfull of useful graphs, charts, tables and images of the technology that help bring the text to life and enhance the report’s readability. The price of the report is $4,350. Additional copies are available for use within your company at an additional charge of $300 per copy.

TABLE OF CONTENTS

INTRODUCTION

Scope

Methodology

About the Author

The Report at a Glance

Executive Summary

The Global IOL Market (Cataract and Refractive)

The Global IOL Market by Region/Economic Status

IOL Pricing Trends

Competitive Landscape

 

CATARACTS

Types of Cataracts

Progression of Cataracts

A Global View of Cataracts

Prevalence of Cataracts by Age

Patients Are Having Cataract Surgery at a Younger Age

The Search for a Cure for Cataracts

The Aging Global Population

Populations Age 60 Years and Older by Country

Baby Boom Generation Reaches 60 in the US

 

CATARACT SURGERY

A Brief History

Today’s Earlier Cataract Removal

Methods of Cataract Extraction

Manual ECCE

Automated ECCE

Phacoemulsification

A Global View of Cataract Surgery

Countries with Greatest Cataract Surgery Volume

Cataract Surgeries Analyzed by Global Region/Economic Status

Forecast for Global Growth in Cataract Surgery

Forecast for Growth in Cataract Surgery by Region/Economic Status

 

PRESBYOPIA AND REFRACTIVE LENS EXCHANGE

Presbyopia

Presbyopic Population in US

Global Presbyopic Population

Refractive Errors

IOLs for Correcting Presbyopia and Refractive Error

Refractive Lens Exchange

 

US CATARACT SURGERY PROVIDERS

Ambulatory Surgery Centers (ASCs)

History of ASCs

ASCs in the US

ASCs by State

Cataract Surgery in ASCs

ASC Growth

Corporate-Owned ASCs

Cataract Surgeries Performed at ASCs

ASC Regulation and Reimbursement

Cataract Surgery in Hospitals

Cataract Surgery Worldwide

Move to Outpatient Surgery

Profile of the Cataract Surgeon

US Cataract and Cataract/Refractive Surgeons

Membership in Professional Organizations

Cataract/IOL Reimbursement

 

THE 2008 GLOBAL IOL MARKET

Market Tiers in the Global IOL Market

Key Competitive Factors

Market Leaders in the Global IOL Market

Competitors’ Market Shares in the US

Competitors’ Market Shares in Western Europe

Competitors’ Market Shares in Japan

Competitors’ Market Shares in Other Wealthy Nations

Competitors’ Market Shares in China

Competitors’ Market Shares in India

Competitors’ Market Shares in ROW Countries

The World’s Most Frequently Used IOL Models

Lens Pricing and Margins

Pricing by Country

Pricing by Material

Pricing by Customer Segment

The Future of IOL Pricing Worldwide

OIG Study Clouds the Future of IOL Pricing at US ASCs

Manufacturing Costs of IOLs

Manufacturing Volume

Manufacturing Efficiency

Labor Rates

Accounting Methods

Lens Design and Price

IOL Technologies that will drive growth through 2013

Presbyopia-Correcting IOLs

A Brief Introduction to Presbyopia-Correcting IOLs

 

MULTIFOCAL PC-IOLS

PC-IOL Mixing and Matching Strategies

Multifocal IOLs on the Market and in Development

Alcon ReStor

AMO ReZoom

AMO Tecnis ZA9003

CZM/Acri.Tec Acri.Twin Multifocal

CZM Acri.Tec Acri.Lisa Multifocal

Hoya

Rayner M-Flex

 

ACCOMMODATING PC-IOLS

The Accommodative Mechanism

Accommodating IOLs on the Market and in Development

Bausch & Lomb/Eyeonics CrystaLens

Acuity C-Well

Adoptics

Akkolens

AMO/Quest Vision IOL

Bausch & Lomb Opal

B&L/Sarfarazi Elliptical Accommodating Intraocular Lens (EAIOL)

EVision/Pixel Optics

HumanOptics AG Akkommodative 1CU

Medennium SmartIOL

Morcher BioComFold 43E

NuLens

Lenstec

PowerVision FluidVision IOL

Tekia

Visiogen Synchrony

Vision Solution Technologies

Accommodating IOLs of Injectable Gel

Bascom Palmer Project

Nishi Eye Project

 

IOLS WITH PREMIUM FEATURES

Aspheric IOLs

Alcon AcrySof IQ (SN60WF)

AMO/Pharmacia Tecnis Z-9000/ZA-9003

Bausch & Lomb SofPort AO

Acri.Tec           

IOLs that Filter Visible Blue or Violet Light

Alcon AcrySof Natural

Hoya AF-1 (UY) and Hoya AF-1 (UV)

Bausch & Lomb SofPort Violet Shield

Medennium Photochromatic IOL

Ophtec Oculaid Orange Series

Toric IOLs

Astigmatism in Cataract Patients

Staar Toric IOL 

CZM/Acri.Tec Acri.Smart Toric

Rayner T-Flex   

Human Optics MicroSil 6116 TU

Micro-Incision IOLs

CZM/Acri.Tec Acri.Smart

Bausch & Lomb Akreos

Santen/AVS

IOLs with Postoperative Adjustment

Market Overview           

Calhoun Vision LAL

Other IOL Design Trends           

Fixed vs. Foldable IOLs

Optic Materials 

Single-piece IOLs vs. Multi-piece IOLs   

Summary of US Surgeon Responses Regarding Most Important IOL Features

 

PHAKIC IOLS

History of Phakic IOLs

Phakic IOL Design Considerations

Phakic IOLs on the Market and in Development

AMO Verisyse/Ophtec Artisan

Staar Visian ICL

Alcon AcrySof Angle-Supported Phakic IOL

Carl Zeiss/IOLTech PRL

OII Phakic 6      

Tekia Kelman Duet        

Hoya/Vision Membrane Technology      

The Phakic IOL Market

Phakic IOL Use Worldwide        

Candidates for Phakic IOLs       

Surgeons Most Likely to Implant Phakic IOLs

Phakic IOL Pricing

 

FORECAST FOR THE GLOBAL IOL MARKET

Premium Monofocal IOL Conversion to Continue

Substantial but Unspectacular Growth for PC-IOLs

Modest RLE IOL Growth Expected

Overview of the Global IOL Market by Region/Economic Status

Forecast for the IOL Market in the United States

Overview

Slowing of Premium Monofocal IOL Conversion

Forecast for Continued Growth in PC-IOLs

Improved PC-IOLs Will Drive RLE Procedures

RLE Pricing in the US

The Phakic IOL Market in the US

Forecast for the IOL Market in Western Europe

Cataract Surgery in Western Europe by Country

Premium Monofocal IOL Growth

PC-IOL Use in Western Europe

The RLE Market in Western Europe

The Phakic IOL Market in Western Europe          

Forecast for the IOL Market in Japan     

Overview

Premium Monofocal IOLs

PC-IOLs in Japan         

The RLE Market in Japan          

The Phakic IOL Market in Japan

Forecast for the IOL Market in Other Wealthy Nations

Overview

Premium Monofocal IOLs

PC-IOLs

The RLE Market in Other Wealthy Nations

The Phakic IOL Market in Other Wealthy Nations

Forecast for the IOL Market in China      

Overview          

The Market for Premium Monofocal IOLs

The Refractive IOL Market in China        

Forecast for the IOL Market in India       

Overview          

The Market for Premium Monofocal IOLs           

The Refractive IOL Market in India          

Forecast for the IOL Market in ROW      

The ROW Market for Premium Monofocal IOLs

ROW’s Refractive IOL Market

 

IOL INJECTORS

Clinical Background

Advantages of Forceps Delivery

Advantages of Injector Delivery

Types of Injectors

Reusable Injectors with a Separate Loadable Cartridge

Disposable Injectors

Desirable Attributes of IOL Injectors

Patent Issues

Injector Makers and Models

Alcon

AMO

Bausch & Lomb

Carl Zeiss/IOLTech Pre-Loaded Injector

Croma Pharma/Corneal

Hoya

Staar

Visiogen

 

COMPANY PROFILES

66 Vision Tech Co. Ltd

Acuity Ltd.

Advanced Medical Optics, Inc.

AJL Ophthalmic, S.A.

Akkolens

Alcon, Inc.

AmSurg Corp.

Appasamy Associates

Aurolab, Inc.

Bausch & Lomb

Benz Research and Development

BIOTECH Visioncare Pvt. Ltd.

Calhoun Vision, Inc.

Care Group Ltd.

Carl Zeiss Meditec, AG

Contamac Ltd.

Croma Pharma/Corneal

Eagle Optics Ltd.

Eurocrystal

EyeKon Medical

Hanita

HCA Inc.

HealthSouth, Corp.

Hoya Corporation

HumanOptics

HyperBranch Medical Technology, Inc.

LCA Pharmaceutical

Lenstec Inc.

Medennium, Inc.

Medicontur Medical Engineering Co.

Mediphacos

Morcher GmbH

NovaMed Eyecare, Inc.

NuLens, Ltd.

Ophthalmic Innovations International (OII)

Ophtec

PhysIOL, SA

Power Vision, Inc.

Rayner Intraocular Lenses Limited

Shah & Shah

SMP Visional

Staar Surgical

Tekia

TLC Vision, Inc.

Visiogen, Inc.

 

INDEX OF TABLES

Total Populations and 60-&-Older Population Segments by Major Country

Advancements in Cataract Surgical Technology

Estimated 2008 Cataract Surgeries by Country

Global Forecast for Cataract Surgery by Region/Economic Status

Refractive Error in the US Population

US ASCs and Dedicated Eye Surgery ASCs by State

Selected Corporate ASC Providers & Cataract Surgeries Performed

Best Eye Hospitals in the US Based on Opinion Research Ranking

Global Demographic Model for Cataract Surgery

US Cataract and Refractive Surgeons

2005 Medicare Reimbursement Rates for Cataract Procedures

Tier-Three IOL Competitors by Country

Start-up IOL Companies

Estimated 2008 Global IOL Sales & Market Shares of Leading Companies

Estimated 2008 Sales & Market Shares of IOL Market Leaders in the US

Estimated 2008 Sales & Shares of IOL Market Leaders in Western Europe

Estimated 2008 Sales & Market Shares of IOL Market Leaders in Japan

Estimated 2008 Sales & Market Shares of IOL Leaders in Other Wealthy Nations

Estimated 2008 Sales & Market Shares of IOL Market Leaders in China

Estimated 2008 Sales & Market Shares of IOL Market Leaders in India

Estimated 2008 Sales & Market Shares of IOL Market Leaders in ROW

Most Commonly Used IOL Models

Average Monofocal IOL Prices in 18 Countries

Estimated 2008 Market Shares of Premium IOL Technologies

Performance of Multifocal IOLs with US FDA Regulatory Approval

Lindstrom’s Staged-Implant IOL-Strength/Weakness Matrix

Multifocal IOLs

Regulatory Status of Multifocal IOLs

ReStor and Visual Disturbances According to FDA Label

Accommodating IOLs

Regulatory Status of Accommodating IOLs

Competitors Producing IOLs with Aspheric Optics, by Aspheric Design

Spherical Aberration Corrected by IOL Model

Current Toric IOL Models

Regulatory Status of Toric IOLs

Micro-incision IOLs

Regulatory Approval of Micro-Incision IOLs

Advantages and Disadvantages of Three Phakic IOL Designs

Phakic IOLs on the Market and in Development

Regulatory Status of Phakic IOLs

Estimated Global 2008 Sales of Phakic IOLs

Phakic IOL Skills by Surgeon Segment

Average Sales Price of Phakic IOL Models

Forecast for the Global IOL Market by Lens Type

Forecast for the Global Premium Monofocal IOL Market

Forecast for the IOL Market in the US

Forecast for the RLE Market in the US

Forecast for the IOL Market in Western Europe

2008 Cataract Surgeries in Western Europe by Country

Forecast for the RLE Market in Western Europe

Forecast for the IOL Market in Japan

Forecast for the Premium Monofocal IOL Market in Japan

Forecast for the RLE Market in Japan

Cataract Surgeries in Other Wealthy Nations

Forecast for the IOL Market in Other Wealthy Nations

Forecast for Premium Monofocal IOLs in the Other Wealthy Nations

Forecast for the RLE Market in Other Wealthy Nations

Forecast for the IOL Market in China

Forecast for Premium Monofocal IOLs in China

Forecast for RLE IOL Surgery in China

Forecast for the IOL Market in India

Forecast for India’s Market in Premium Monofocal IOLs

Forecast for RLE IOL Procedures in India

Forecast for the IOL Market in ROW

The Most Attractive ROW IOL Markets

Forecast for Premium Monofocal IOLs in ROW

Forecast for RLE IOL Procedures in ROW

The Most Common Types of IOL Injectors

IOL Injectors by IOL Company and Injector Style

Forecast for Disposable Injector Sales by Country/Region

 

INDEX OF FIGURES

Forecast for Global IOL Revenue (Cataract and Refractive)

Forecast for Global IOL Market by Region/Economic Status

IOLs Implanted in 2008 by Region/Economic Status

2008 IOL Revenues by IOL Type and by Region/Economic

2008 Market Shares of IOL Competitors

Incidence of Cataract Type (Location in the Eye)

Prevalence of Cataracts in the US by Age Group

Cataracts in the US by Age Group (2008)

Percentage of Global Population 60 Years and Older in 2008 and 2020

Forecast for US Population Growth by Age Group

Forecast for US Cataract Procedures by Type

Cataract Surgeries by Global Region/Economic Status

Change in Accommodative Amplitude by Age

Presbyopic Population in US

Forecast for Growth of the Global Presbyopic Population

Diagram of Refractive Error, Presbyopia and Cataract

ASCs by Specialty

2008 US Cataract Surgeries by Location

Cataract Procedures by Surgery Locations

Cataract Surgeries by ASC Ownership

ASC and Hospital Outpatient Reimbursements for CPT Code 66984

Cataract Surgeon’s Membership in Professional Organizations

Cataract Surgeons by Types of Practice

Cataract Surgeons’ in Group Practices by Group Size

Cataract Surgeons Grouped by Annual Cataract Procedure Volume

Sources of Revenue for Cataract Surgeons

Marketing Methods Used for Cataract Practices

Medicare-Covered vs. Privately-Covered Cataract Surgeries

Physician’s Reimbursement for CPT Code 66984 by Year

Market Share by Company

Global IOL Market Revenues by Market Leaders and All Others (2000-2008)

Market Share by Revenue Tiers

Key Products as a Percent of Surgeons’ Cross-Merchandizing Arrangements

Global Monofocal IOL and PC-IOL Revenues, 2001-2008

PC-IOL Mix and Match Frequency         

The Wearing of Glasses with the ReStor and Other IOLs

CrystaLens Monocular UCVA, One Year Post-Op

Monocular Intermediate Vision through Distance Correction, One Year Post-Op

UCVA Binocular Near, Intermediate and Distance, 11 to 15 Months Post-Op

Uncorrected Near Visual Acuity with Monocular CrystaLens AT-45, 5.0, and HD-100         

NuLens Accommodative Process in Sulcus

Market Share of Aspheric Monofocal IOL Optics in the US, 2004–2008

Market Share of IOLs with Blue-Light Filtering Optics in the US, 2004–2008

Frequency of Surgical Treatments for Astigmatism

Global Market Share of Micro-incision IOLs, 2004–2008

Calhoun LAL Light Adjustment Principle

Calhoun LAL

Market Shares for Foldable and Fixed IOLs in the US

Market Share for IOL Optic Materials in the US (2001-2008)

US Market Shares for Single-piece and Multi-piece IOLs

Ratings for IOL Features

Estimated 2008 Phakic Implants in Western Europe by Country

Severely Myopic Population in the US

US Surgeons Offering or Planning to Offer Phakic IOLs

Forecast for Multifocal and Accommodating PC-IOL Units & Share

Forecast for Global RLE

Forecast for Global IOL Market Revenues by Region/Economic Status

Forecast for the US Premium Monofocal IOL Market

Forecast for the Multifocal and Accommodating PC-IOL Markets in the US

Average Patient Costs for LASIK, Cataract and RLE (2006)

Forecast for Premium Monofocal IOL Growth in Western European

Forecast for Growth in Multifocal and Accommodating PC-IOL Models

2007 Phakic IOL Use in Western Europe by Country

Forecast for PC-IOLs in Japan

Forecast for PC-IOLs in Other Wealthy Nations

IOL Market in China, Unit Share by Material

Forecast for the PC-IOL Market in China

IOL Unit Share in India by Type of IOL

Forecast for the PC-IOL Market in India

Forecast for the PC-IOL Market in ROW

Hoya I-Sert Pre-Loaded Disposable Injector System